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Search Results for " high molecular weight kininogen "

1

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T76710 Lanadelumab
Lanadelumab (SHP643), a humanized IgG1 monoclonal antibody, targets plasma kallikrein (pKal) with a K i value of 0.12 nM, effectively inhibiting both its free form and its interaction with high molecular weight kininogen...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00734 KNG1 Protein, Human, Recombinant (His) Human HEK293 Cells
Kininogen-1 is a secreted protein which contains three cystatin domains. There are two alternatively spliced forms, designated as the high molecular weight (HMW) and low MW (LMW) forms. Kininogen-1 plays a critical role ...
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His) Human HEK293 Cells
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPK-01271 Coagulation factor XI Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a co...
TMPH-01581 KRT1 Protein, Human, Recombinant (His) Human E. coli
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/H...
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